View tty used by applications
Try to use the command lsof.
lsof /dev/ttyX
To get the PID directly, use:
lsof -Fp /dev/ttyX
Mac OS analog to /dev/ttyUSBxx
OS X doesn't create a /dev entry for raw access to USB devices, and there's no way to access them as TTY devices.
Partly this is a different in philosophy between Linux and BSD, partly it's a difference in driver-writing technology, and partly it's a matter of already having a well-defined hierarchy (the IOKit Registry) that would have to be mapped to the /dev hierarchy in some complicated way.
At any rate, if you want to learn how you should access USB devices on a Mac, start with QA1370. If you're looking to do a quick port of some linux code without actually learning IOKit/IOUSB, it's probably going to be impossible. If you're looking for something else, you'll need to give more info about what you're trying to do.
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