How to Uninstall Python2.6

How to uninstall Python 2.7 on a Mac OS X 10.6.4?

Do not attempt to remove any Apple-supplied system Python which are in /System/Library and /usr/bin, as this may break your whole operating system.

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NOTE: The steps listed below do not affect the Apple-supplied Python 2.7; they only remove a third-party Python framework, like those installed by python.org installers.

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The complete list is documented here. Basically, all you need to do is the following:

1. Remove the third-party Python 2.7 framework

    sudo rm -rf /Library/Frameworks/Python.framework/Versions/2.7
   

2. Remove the Python 2.7 applications directory

    sudo rm -rf "/Applications/Python 2.7"
   

3. Remove the symbolic links, in /usr/local/bin, that point to this Python version. See them using

    ls -l /usr/local/bin | grep '../Library/Frameworks/Python.framework/Versions/2.7' 
   

and then run the following command to remove all the links:

    cd /usr/local/bin/
    ls -l /usr/local/bin | grep '../Library/Frameworks/Python.framework/Versions/2.7' | awk '{print $9}' | tr -d @ | xargs rm

4. If necessary, edit your shell profile file(s) to remove adding /Library/Frameworks/Python.framework/Versions/2.7 to your PATH environment file. Depending on which shell you use, any of the following files may have been modified:
   ~/.bash_login, ~/.bash_profile, ~/.cshrc, ~/.profile, ~/.tcshrc, ~/.zshrc, and/or ~/.zprofile.

How to completely uninstall python 2.7.13 on Ubuntu 16.04

caution : It is not recommended to remove the default Python from Ubuntu, it may cause GDM(Graphical Display Manager, that provide graphical login capabilities) failed.

To completely uninstall Python2.x.x and everything depends on it. use this command:

sudo apt purge python2.x-minimal

As there are still a lot of packages that depend on Python2.x.x. So you should have a close look at the packages that apt wants to remove before you let it proceed.

Thanks, I hope it will be helpful for you.

Unable to uninstall Python 2.7.18 via CLI (msi file/windows)

Thanks to @Stein-Asmul I found a solution here: Uninstalling an MSI file from the command line without using msiexec

Instead of calling my msi file like python-2.7.18.msi /uninstall - I am now calling msiexec.exe from Windows:
msiexec.exe /x "D:\X\python-2.7.18.msi" /QN REBOOT=R

This in my case, works perfect

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